Authors - Darrel A. Cardana, Ethel Zean M. Anosa, Angeline B. Elegio, Jes Maries Mendez, Ivy Corazon Mangaya-ay Abstract - Agri-Aqua Technology Business Incubators (ATBIs) play an important role in promoting innovation, entrepreneurship, technology commercialization, and institutional collaboration within higher education institutions. This study assessed the operational performance and institutional development of the BISU Agri-Aqua Technology Business Incubator (ATBI). Specifically, the study evaluated the accomplishments of the incubator in terms of personnel capacitation, partnership and linkage development, awareness and promotional activities, incubation services, technology incubation initiatives, intellectual property generation, and policy institutionalization. The study also examined the capacitybuilding activities, partnership initiatives, intellectual property outputs, and the problems and strategic solutions encountered during implementation. The study employed a descriptive-evaluative research design utilizing documentary analysis of the official accomplishment report and supporting institutional documents of the BISU ATBI. Frequency counts, percentage analysis, and thematic analysis were utilized in analyzing the collected data. The findings revealed that the BISU ATBI successfully implemented several operational and institutional initiatives. The incubator conducted seventeen (17) trainings and workshops, forged twelve (12) MOUs with incubatees and six (6) institutional partnerships, conducted eight (8) awareness seminars, developed ten (10) business plans, filed ten (10) trademarks and five (5) copyrights, and enrolled seventeen (17) incubatees in the incubation program. However, only two (2) technologies were successfully co-incubated despite the target of ten technologies, indicating challenges in technology commercialization and adoption. The study also identified regulatory hurdles, technology readiness concerns, partnership issues, and low technology adoption as major implementation challenges. Overall, the findings indicate that the BISU ATBI established a strong operational and institutional foundation for technology business incubation, although continuous enhancement of commercialization and technology adoption initiatives remains necessary.